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Cosmos in Action
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Epic Research

ED Visits for Motor Vehicle Crashes Associated with Elevated Risk of Subsequent Firearm Injury for Young Male Patients
Male patients aged 10 to 15 who had an ED visit for a motor vehicle crash (MVC) were as much as four times as likely to experience a subsequent firearm injury compared with those whose ED visit was for a fall, in some parts of the United States.

Cardiovascular Event Risk Increases More Sharply for Men Than Women at Very Low Average Blood Pressure
The risks of myocardial infarction (MI), ischemic stroke, and hemorrhagic stroke are increased for patients with high or low average systolic blood pressure (BP). The risks are greater at very low systolic BP than at very high systolic BP.

Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some Weight Loss
At 24 months post-cessation, 56% of semaglutide, 52% of liraglutide, and 55% of tirzepatide patients kept the weight off or lost additional weight.

2025 Hypertension Guideline Update Modestly Expands Stage 1 Treatment Eligibility, with Net Increases Concentrated Among Older and Female Patients
Among adults aged 40–79 with stage 1 hypertension, treatment eligibility rose modestly from 45.2% under the 2017 guideline to 47.0% under the 2025 guideline. Overall, 3.2% of patients would be treated differently under the new guideline (2.5% gained eligibility, 0.7% lost eligibility).


