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Cosmos

Cosmos is a dataset created in collaboration with a community of health systems using Epic and is designed to improve patient care. By combining their data, participating organizations and Epic can make new discoveries and advance medicine. Cosmos also powers tools at the point of care, providing insights to clinicians that are tailored to the patient in front of them.
More about Cosmos →

Cosmos Community

2,358
Hospitals
310 Million
Patients
52.5K
Clinics
Meet a few of our Cosmos community members:
NYU Langone Health
Infirmary Health System
UNC Health Care System
University of Utah Health
Corewell Health
Connecticut Children's
SGMC Health
Learn more about the Cosmos community →

Cosmos in Action

Cosmos at the Point of Care

The vision for Cosmos has always included empowering providers with data to improve care for their patients. With our recently released and ongoing development of Cosmos-enabled features, providers can use attributes from the patient in front of them to review personalized insights they can use alongside their own expertise and experience to partner with their patient on shared decision-making. Some examples include:

Best Care Choices

To further evidence-based care, Best Care Choices for My Patient shows providers insights into how similar patients responded to the treatments they are considering, right at the point of care. Physicians will be able to explore the collective knowledge from millions of clinical decisions to see treatments and resulting outcomes for patients like the one in front of them.

Look-Alikes

Very rare conditions and medical mysteries often result in limited evidence for a physician to draw from when determining a course of action or treatment for their patient. Look-Alikes enables providers to connect with other providers across the Cosmos community who might have experience with patients with a similar constellation of symptoms or condition so they can collaborate on care.

Condition-Specific Growth Charts

Publications Using Cosmos

Researchers in the Cosmos community have published dozens of papers using Cosmos data.
Some statistics on research publications that used Cosmos data:
259
Publications
167
Journals
71
Organizations
259
Publications

Epic Research

While traditional research continues to serve as a primary source of information to inform clinical practice, we identified a need for a new kind of analysis focused on getting good data out quickly to clinicians and decision-makers where it can make a difference. To address this need, we launched Epic Research. Using our dual-team process, Epic Research teams evaluate timely, topical, and relevant questions and make findings available to the public at no-cost at EpicResearch.org.
Likelihood of Early-Onset Colorectal Cancer by Pre-Screening AST and ALT Level

Low AST and ALT Levels Are Associated with Higher Likelihood of Early-Onset Colorectal Cancer in Adults Under 45

Among adults aged 18–44 undergoing a first colorectal cancer (CRC) screening, a pre-screening AST below 14 U/L was associated with a 65% higher likelihood of an early-onset CRC diagnosis, and an ALT below 14 U/L with a 68% higher likelihood, each compared with patients whose values fell in the range of 14–29 U/L.

Orlando Health
Standard growth charts often don't account for disease-specific nuances that can influence a child's development. When a chronic condition affects a child's growth, Cosmos enables growth charts that show clinicians and family members how the child is progressing relative to others with the same disease.
167
Journals
71
Organizations
Browse all publications →
Read the full brief on Epic Research →
Hormone Therapy Use Rate Over Time by Age Group

Hormone Therapy Use Nearly Doubled Since 2017, Led by Women in Their Late 40s and Early 50s

Among women seen in outpatient care, the rate of hormone therapy (HT) use rose from 1.7% in January 2017 to 3.6% in April 2026, a near-doubling. The increase was modest through 2022 and then accelerated sharply from 2023 onward.

Read the full brief on Epic Research →
Quarterly Rate of Diagnosed Gambling Disorder by State Sports Betting Legalization Status

Gambling Disorder Diagnoses Have Risen More Than 60% in States That Legalized Sports Betting

Among adult patients living in states that have legalized sports betting, the quarterly rate of diagnosed gambling disorder rose from 3.0 per 100,000 patients in Q1 2018 to 4.8 per 100,000 in Q1 2026, around a 61% increase.

Read the full brief on Epic Research →
Change in Emergency and Urgent Care Injuries Around Independence Day by Injury Type

Hazardous Holidays? Injury Patterns in Urgent and Emergency Care Vary by Injury Type and Time of Year

Among the U.S. holidays studied, Independence Day had the largest overall increase in injuries, averaging 5,418 more injuries than baseline over the three-day holiday window. Fireworks/blast injuries rose to 22 times baseline (1,187 more cases), burns were 1.8 times baseline (1,267 more cases), and fire/smoke exposures were 2.3 times baseline (383 more cases).

Read the full brief on Epic Research →
Explore more studies and data insights from Cosmos
on Epic Research →