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Cosmos in Action
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Epic Research

ED Visits for Motor Vehicle Crashes Associated with Elevated Risk of Subsequent Firearm Injury for Young Male Patients
Male patients aged 10 to 15 who had an ED visit for a motor vehicle crash (MVC) were as much as four times as likely to experience a subsequent firearm injury compared with those whose ED visit was for a fall, in some parts of the United States.

Cardiovascular Event Risk Increases More Sharply for Men Than Women at Very Low Average Blood Pressure
The risks of myocardial infarction (MI), ischemic stroke, and hemorrhagic stroke are increased for patients with high or low average systolic blood pressure (BP). The risks are greater at very low systolic BP than at very high systolic BP.

Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some Weight Loss
At 24 months post-cessation, 56% of semaglutide, 52% of liraglutide, and 55% of tirzepatide patients kept the weight off or lost additional weight.

Most Adults Without Diabetes Maintain Their GLP-1 Weight Loss Through a Second Year, Though Gradual Regain Begins After the One-Year Mark
Among adults without diabetes who lost weight during their first year on a GLP-1 medication, most sustained that loss into the second year. At the two-year mark, 53.1% of semaglutide patients and 52.9% of tirzepatide patients had maintained their weight within a narrow band of their one-year weight, and a further 31.9% (semaglutide) and 39.3% (tirzepatide) had lost even more.


